The therapeutic use of the relaxation response in stress-related diseases.
نویسندگان
چکیده
The objective of this work was to investigate a possible (therapeutic) connection between the relaxation response (RR) and stress-related diseases. Further, common underlying molecular mechanisms and autoregulatory pathways were examined. For the question of (patho)physiology and significance of RR techniques in the treatment of stress-related diseases, we analyzed peer-reviewed references only. The RR has been shown to be an appropriate and relevant therapeutic tool to counteract several stress-related disease processes and certain health-restrictions, particularly in certain immunological, cardiovascular, and neurodegenerative diseases/mental disorders. Further, common underlying molecular mechanisms may exist that represent a connection between the stress response, pathophysiological findings in stress-related diseases, and physiological changes/autoregulatory pathways described in the RR. Here, constitutive or low-output nitric oxide (NO) production may be involved in a protective or ameliorating context, whereas inducible, high-output NO release may facilitate detrimental disease processes. In mild or early disease states, a high degree of biological and physiological flexibility may still be possible (dynamic balance). Here, the therapeutic use of RR techniques may be considered particularly relevant, and the observable (beneficial) effects may be exerted via activation of constitutive NO pathways. RR techniques, regularly part of professional stress management or mind/body medical settings, represent an important tool to be added to therapeutic strategies dealing with stress-related diseases. Moreover, as part of 'healthy' life-style modifications, they may serve primary (or secondary) prevention. Further studies are necessary to elucidate the complex physiology underlying the RR and its impact upon stress-related disease states.
منابع مشابه
Comparing the Efficacy of Three Therapeutic Methods of Emotional Expression, Mental and Combined Relaxation in Reducing Perceived Stress
متن کامل
Systemic Inflammatory Response Syndrome Due to Surgery and its Effective Therapeutic Approaches
Introduction: Various lesions trigger an inflammatory response in the host body. These injuries include surgical stress Surgery exerts stress on the body. Systemic inflammatory syndrome is a reflection of the degree of surgical stress and as a system of assessing the severity of postoperative stress. Regular complexes of inflammatory polypeptide molecules contribute to the development of this i...
متن کاملتغییرات مانومتری آنورکتال به دنبال درمان کودکان مبتلا به یبوست مزمن فانکشنال
Background and purpose: Anorectal manometry is a suitable diagnostic method in children with chronic constipation and could provide useful information on the causes of constipation. This study was done to evaluate the therapeutic response of standard treatment and improve the diagnostic method via assessment of manometric parameters before and after the standard treatment. Materials and method...
متن کاملHomocysteine Induces Heme Oxygenase-1 Expression via Transcription Factor Nrf2 Activation in HepG2 Cells
Background: Elevated level of plasma homocysteine has been related to various diseases. Patients with hyperhomocysteinemia can develop hepatic steatosis and fibrosis. We hypothesized that oxidative stress induced by homocysteine might play an important role in pathogenesis of liver injury. Also, the cellular response designed to combat oxidative stress is primarily controlled by the transcripti...
متن کاملEffects of Taurine, Sestrin 2 and Phyllanthin on coronary artery diseases
Heart failure is a growing epidemic in the worldwide. Atherosclerosis is a major mechanism of cardiovascular disease including myocardial infarction and peripheral arterial disease. Moreover, it causes many diseases and deaths around the world. Atherosclerosis, like coronary artery disease (CAD), is associated with inflammation and oxidative stress. The current article has been collected the s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Medical science monitor : international medical journal of experimental and clinical research
دوره 9 2 شماره
صفحات -
تاریخ انتشار 2003